Can Type 2 Diabetes Be Reversed? Proven Food & Role of GLP-1

Type 2 diabetes (T2D) is a chronic condition characterized by insulin resistance and impaired insulin secretion, leading to elevated blood glucose levels. Traditionally considered a lifelong disease, recent research has challenged this view, suggesting that remission or even reversal is possible under certain conditions. Answering a common question, ‘Can Type 2 Diabetes Be Reversed?’, the latest research in this regard is promising, and a case from China, showing a stem cell therapy for type 1 diabetes cure, is turning hopes stronger.

What is Diabetes?

Diabetes mellitus is a group of diseases that affect how the body uses blood sugar (glucose). In T2D, the body either becomes resistant to insulin or doesn’t produce enough insulin, leading to elevated blood glucose levels. Over time, high blood glucose can lead to serious complications, including heart disease, nerve damage, and kidney failure.

Diabetes Etiology and Possibility of Reversal

The development of T2D involves a combination of genetic and environmental factors. Obesity, physical inactivity, and poor diet are significant contributors to the onset of the disease. Recent studies have shown that T2D can be reversed, particularly when diagnosed early and managed aggressively. Reversal often refers to the normalization of blood glucose levels without the need for diabetes medication. However, this does not imply a permanent cure, as the risk of relapse remains if lifestyle changes are not maintained.

Is It Possible to Reverse Diabetes Naturally?

Yes, natural interventions can play a significant role in reversing T2D. Research has demonstrated that weight loss, a diabetes reversal diet, and physical activity can lead to remission. For instance, a study published in The Lancet found that nearly half of participants who lost an average of 30 pounds through a strict diet plan achieved remission from T2D. Additionally, as per a study shared by Medical News Today, a low-carb diet has been shown to reverse T2D in 51% of participants.

According to the JMH, ‘low-carbohydrate diet varies in the literature, and the majority says that anything over 130 g – 150 g per day cannot be regarded as a low carbohydrate diet.’

Foods to Reverse Diabetes:

The core components of diabetes management revolve around diet, exercise, medication, and education. And as per these core components, when shifting to a low-carbohydrate diet (LCD), a nutrient-dense diet is recommended, e.g., non-starchy vegetables, eggs, and oily fish.
The following are the two tables with the best diet to reverse type 2 diabetes. Please consult your healthcare specialist before starting a strict diet plan.

Foods with Very Low Carbohydrates (Non-Starchy Vegetables, Eggs, Oily Fish, Dairy Fats)

These foods are excellent for low-carb diets, providing minimal carbohydrates, moderate to high protein, and healthy fats.

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Foods with Moderate Carbohydrates, High Fiber, Protein, and Healthy Fats

These foods offer a balance of carbohydrates, fiber, protein, and healthy fats, suitable for a balanced diet.

Notes:

• Carbohydrates: Total carbohydrates per 100g serving.
• Fiber: Dietary fiber content per 100g serving.
• Protein: Protein content per 100g serving.
• Fat: Total fat content per 100g serving.

These values are averages and can vary based on specific varieties and preparation methods. For precise dietary planning, it’s recommended to consult detailed nutritional databases or food labels.

Latest Research on Reversing T2D

While specific TEDx talks may not have addressed the reversal of T2D, various university-led studies have contributed to this field. For example, research from Newcastle University demonstrated that significant weight loss could lead to the remission of T2D. These findings have been pivotal in reshaping the understanding of T2D and its potential for reversal.

Did you know?

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What Does the Latest Research Say About Non-Responding Insulin?

Recent studies have highlighted that insulin resistance can be managed and even reversed through lifestyle interventions and medications. For instance, as per an article shared by Springer, early insulin therapy has been shown to protect against beta cell loss in mouse models. This suggests that the timely and appropriate use of insulin can prevent the progression of T2D.

Can Insulin Resistance Be Permanently Treated? Concept of Beta Cell Regeneration

Insulin resistance can be effectively managed through lifestyle changes, medications, and in some cases, surgical interventions. Regarding beta cell regeneration, recent studies have shown promising results. For example, a two-drug combination in mice led to a 700% increase in insulin-producing cells within three months. While these findings are preliminary, they offer hope for future treatments aimed at regenerating beta cells in humans.

Role of Novel Anti-Obesity GLP-1 in Reversing Diabetes or Maintaining Insulin Resistance

Glucagon-like peptide-1 (GLP-1) receptor agonists, such as semaglutide and liraglutide, have shown efficacy in managing T2D. These medications work by enhancing insulin secretion, inhibiting glucagon release, and promoting satiety, leading to weight loss. A study published by the FDA highlighted the approval of a generic version of liraglutide for lowering blood sugar in T2D patients. Additionally, tirzepatide, a dual GLP-1 and GIP receptor agonist, has demonstrated superior efficacy in reducing Hba1c levels and body weight compared to other treatments.

Conclusion

While T2D is a serious condition, recent research offers hope for reversal, especially when interventions are implemented early and maintained consistently. The cure for diabetes requires lifestyle changes, medical treatments, and, in some cases, surgical interventions. Adopting such a multi-dimensional approach may cure your diabetes, however, ongoing management is essential to sustain these benefits and prevent reversion. To answer a common question, ‘Which is worse, type 1 or 2 diabetes?’, well, long-term prevalence of any type of diabetes is harmful; however, the worst among type 1 and type 2 is type 1 diabetes, also known as insulin-dependent diabetes.