Freestyle Libre 2 vs 3: A Clear User-Friendly Comparison

A Continuous Glucose Monitor (CGM) is a wearable device that continuously measures glucose levels in the interstitial fluid beneath the skin. Both Freestyle Libre 2 and 3 CGM sensors use a tiny microfilament inserted just under the skin to continuously monitor glucose levels. These sensors come with a built-in transmitter that automatically sends real-time data. In the Freestyle Libre 2 vs 3 comparison, one major upgrade is device compatibility—while older CGM kits required a dedicated receiver, the latest models are fully smartphone-compatible and can still be paired with handheld CGM receivers if preferred.

FreeStyle Libre 2 and Libre 3 can both be used by anyone aged 4 and above who is living with type 1, type 2 or gestational diabetes. However, the Freestyle Libre 3 Sensors take the edge on accuracy, size, and some more features. Here we have not only covered Freestyle Libre 2 vs 3 but have also shed some light on the newer variants, which may help people who take insulin.

Sensor Size and Design

The sensor is the core component of any CGM system.

• FreeStyle Libre 2 Sensors: Measures 5 mm in height and 35 mm in diameter, weighing approximately 5 grams.
• FreeStyle Libre 3 Sensors: Significantly smaller at 2.9 mm in height and 21 mm in diameter, with a weight of 1 gram.

The Libre 3’s compact design makes it the smallest and thinnest sensor available, enhancing comfort and discretion for users.

Connectivity and Data Syncing

Both systems offer wireless data transmission, but with notable differences:

• Libre 2: Utilises Bluetooth Low Energy (BLE) technology to transmit data to a reader or smartphone app.
• Libre 3: Employs Bluetooth technology for automatic, real-time data transmission to the FreeStyle Libre 3 app, eliminating the need for manual scanning.

The Libre 3’s continuous data streaming provides more immediate insights into glucose trends.

Battery Life

Battery life is crucial for uninterrupted glucose monitoring:

• Libre 2: Sensor lasts up to 14 days; reader’s battery life is approximately 4 days with continuous sensor connection.
• Libre 3: It also lasts up to 14 days; the reader’s battery life is around 4 days.

Both systems require regular charging to ensure continuous monitoring.

Accuracy and MARD (Mean Absolute Relative Difference)

Accuracy is paramount in CGM systems:

• Libre 2: With a 9.3% MARD value, it offers reliable glucose readings suitable for daily management.
• Libre 3: With a 7.8% MARD value, it provides improved accuracy, enhancing the reliability of glucose readings.

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App Integration and Features

Both systems integrate with mobile applications, but with differences in functionality:

• Libre 2: Compatible with the FreeStyle LibreLink app, allowing users to scan the sensor for glucose readings.
• Libre 3: Fully integrated with the FreeStyle Libre 3 app, offering real-time glucose readings, customizable alerts, and data sharing capabilities.

Freestyle Libre 2 vs 3: Side-by-Side Comparison 

Important Update: Discontinuation Notice

Abbott has announced that both FreeStyle Libre 2 and Libre 3 sensors will be discontinued in the USA by September 30, 2025.

Conclusion

While Libre 2 and Libre 3 both have been market leaders. The Freestyle Libre 3 sensors boast a lower MARD value, depicting their higher accuracy and have won the crown of being the world’s first smallest sensor. Moreover, if an individual requires insulin boluses, they may find it useful to go for Freestyle Libre 2 Plus or Freestyle Libre 3 Plus sensors – these newer variants not only have great accuracy but are automatic insulin delivery (AID) compatible as well.

 Frequently Asked Questions